Tylenol (acetaminophen)

Drug Class

Over the counter analgesic

Indication for Use

Pain and fever reduction
Allergy, cold, cough and flu symptom relief


Liver failure


An over-the-counter (OTC) medication, Tylenol is used to treat symptoms of many illnesses, including the common cold and flu. Tylenol and related products are manufactured by McNeil PPC, Inc., a subsidiary of Johnson & Johnson.

The active ingredient in Tylenol is acetaminophen, which is linked to acute liver failure damage. Overdose can occur when an individual takes an OTC drug containing acetaminophen and a prescription drug containing it as well. However, even when this product is taken as directed, liver failure can occur.

Over the years, McNeil has made numerous changes to Tylenol’s warning labels in response to the risk of liver failure.

In April 2013, the United States District Panel on Multidistrict Litigation transferred claims to the U.S. District Court, Eastern District of Pennsylvania creating MDL 2436.